Weariness, pain weariness or tiredness

Ra say:

81.5 Weariness of the time/space nature may be seen to be that reaction of transparent or pure vibrations with impure, confused, or opaque environs.

And if vibrations are

47.3 The vibratory rates are not to be understood as the same in positive and negative orientations. They are to be understood as having the power to accept and work with intelligent infinity to a certain degree or intensity.

it means the more you accept and work with intelligent infinity the more weariness you have when contacting confused or opaque environs and nothing of which we are aware may be done.